Basic Medical Endocrinology 4th Edition, Maurice Goodman provides first year medical students with a basic knowledge of regular endocrine physiology cellular and molecular levels and prepares them for extra advanced studies of endocrine pathology and therapies. It's an introductory text that provides a strong foundation of background information for the aspiring clinician, or for college students planning to progress in a course that investigates a broader vary of organisms.
This text continues to have the identical focus as previous editions-the integrative and regulatory roles of the endocrine programs, with up-to-date coverage of essential advances in cellular and molecular mechanisms. The integrative focus of this book reflects the over 40 years of experience of the editor with teaching physiology and endocrinology to medical students. It's precisely the integrative focus that makes this textbook so valuable.
The primary chapters provide an overview of the principles of hormone structure and performance and the roles of the primary endocrine glands. The remaining chapters take care of how hormones serve to regulate advanced physiological functions, comparable to fuel metabolism, regulation of salt and water stability, calcium stability, growth and reproduction. These chapters present an integrative framework for understanding how these capabilities reply to challenges from the internal or external environment.
Immediately noticeable in the fourth edition is the rich look of the book with its new coloration figures (300 whole) that make many of the illustrations simpler to understand. This book continues to be very readable, concise and provides sufficient basic knowledge of how a selected system works with out getting slowed down in the unmanageable details of intracellular signaling cascades or regulation of gene transcription. It provides the framework on which a student can add extra advanced detail of a particular cell or tissue or of a hormone-related disease.
An essential change in this book is the rise in coverage of the regulation of fuel metabolism, which is covered in 3 chapters: Hormones of the GI Tract (utterly new chapter), The Pancreatic Islets, and Hormonal Regulation of Gasoline Metabolism. This improve in coverage is acceptable and reflects the very sturdy emphasis on this space of analysis over the past 10 years. The rise in obesity and diabetes in our inhabitants has supplied the stimulus for this research, which has led to a sizable growth in information of this very complicated area.
Revisions of other chapters capture most new advances, without tremendously expanding the length of the text. Nevertheless, managing this feat requires leaving out some information. For example, there isn't a point out of the discovery of kisspeptin, which is made in neurons within the hypothalamus. Kisspeptin is now considered to be the primary regulator of GnRH neurons and reproductive function. Also, it is likely that a future edition will think about adipose tissue as an endocrine organ, reflecting the array of hormones synthesized by adipocytes and its significance in glucose homeostasis and the metabolic syndrome.
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